Expiration date: 02/2026
The composition and form of issue:
1 ml of the emulsion for I/V injection contains propofol 10 mg, and soy oil, medium chain triglycerides, glycerol, egg lecithin and sodium oleate in vials of 20 ml, in a contour acheikova package 5 ampoules, or in vials of 50 ml, in a carton 1 contour cell pack or 1 bottle.
Method of application and dose:
In/in, dose set individually.
General anesthesia for adults.
Induction of anesthesia: adults: 20-40 mg every 10 s until signs of anesthesia. Patients under the age of 55 years usually require 1.5 to 2.5 mg/kg, over 55 years of age and patients III and IV classes ASA, especially with heart failure, the dose should be reduced to 1 mg/kg and to decrease the rate of injection (20 mg every 10 seconds). Children over 3 years — slowly until the onset of clinical signs of anesthesia. Dose adjustments in accordance with age and (or) body weight of the child. Children older than 8 years the likely dose of 2.5 mg/kg. younger Children may require higher doses. Children of III and IV classes ASA recommended lower dose. Not recommended for use in children under 3 years.
Maintain anesthesia: adults — in the form of prolonged infusions or repeated bolus injections. Under the continuous infusion dose is usually in the range of 6-12 mg/kg. Older patients, patients with severe General condition, patients III and IV classes ASA and patients with hypovolemia, the dose is reduced to a minimum of 4 mg/kg/h Bolus injection 25 to 50 mg. Children older than 3 years — in the form of a continuous infusion or bolus injection, usually provided satisfactory anesthesia with a speed of introduction of 9-15 mg/kg/h.
The achievement of the sedative effect in intensive care patients on mechanical ventilation recommended continuous infusion at a speed of 0,3 to 0,4 mg/kg/h for diagnostic and surgical procedures, depending on the clinical picture, usually 0.5–1 mg for 1-5 minutes to achieve effect and 1.5–4.5 mg/kg/h to maintain. To quickly achieve deep sedation — bolus 10-20 mg.
Can not be used in children up to 16 years in surgical and diagnostic procedures to achieve sedation.
You should not use the drug during pregnancy and lactation, and as an anesthetic in obstetrics. Do not mix with other injectable solutions, except 5% glucose solution, lidocaine solution for injection solution fentanyl for injection.
